Skip to main content

Articles

Page 37 of 76

  1. Cancer stem-like traits contribute to prostate cancer (PCa) progression and metastasis. Deciphering the novel molecular mechanisms underlying stem-like traits may provide important insight for developing novel...

    Authors: Jing Hu, Feifei Sun, Weiwen Chen, Jing Zhang, Tao Zhang, Mei Qi, Tingting Feng, Hui Liu, Xinjun Li, Yuanxin Xing, Xueting Xiong, Benkang Shi, Gengyin Zhou and Bo Han
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:227
    Content type: Research Published on:

  2. A novel paradigm in tumor biology suggests that osteosarcoma (OS) chemo-resistance is driven by osteosarcoma stem cell-like cells (OSCs). As the sensitivity of only a few tumors to epidermal growth factor rece...

    Authors: Tian Wang, Dexing Wang, Lian Zhang, Ping Yang, Jing Wang, Qi Liu, Fei Yan and Feng Lin
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:226
    Content type: Research Published on:

  3. Triple-negative breast cancer (TNBC) is often aggressive and associated with a poor prognosis. Due to the lack of available targeted therapies and to problems of resistance with conventional chemotherapeutic a...

    Authors: Jinjiao Hu, Yanhao Zhang, Xiuxing Jiang, Hongwei Zhang, Ziyi Gao, Yunong Li, Ruoqiu Fu, Lirong Li, Jie Li, Hongjuan Cui and Ning Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:225
    Content type: Research Published on:

  4. The bcr-abl fusion gene encodes BCR-ABL oncoprotein and plays a crucial role in the leukemogenesis of chronic myeloid leukemia (CML). Current therapeutic methods have limited treatment effect on CML patients w...

    Authors: Zhenhong Luo, Miao Gao, Ningshu Huang, Xin Wang, Zesong Yang, Hao Yang, Zhenglan Huang and Wenli Feng
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:224
    Content type: Research Published on:

  5. Emerging evidence supports the pivotal roles of adipocytes in breast cancer progression. Tumour induced beige/brown adipose tissue differentiation contributes to the hypermetabolic state of the breast cancer. ...

    Authors: Qi Wu, Juanjuan Li, Zhiyu Li, Si Sun, Shan Zhu, Lijun Wang, Juan Wu, Jingping Yuan, Yimin Zhang, Shengrong Sun and Changhua Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:223
    Content type: Research Published on:

  6. The third generation Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) osimertinib has been initially approved for T790M positive Non-Small Cell Lung Cancer (NSCLC) and more recently for ...

    Authors: Silvia La Monica, Roberta Minari, Daniele Cretella, Lisa Flammini, Claudia Fumarola, Mara Bonelli, Andrea Cavazzoni, Graziana Digiacomo, Maricla Galetti, Denise Madeddu, Angela Falco, Costanza Annamaria Lagrasta, Anna Squadrilli, Elisabetta Barocelli, Alessandro Romanel, Federico Quaini…
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:222
    Content type: Research Published on:

  7. Extracellular signal-regulated kinases (ERKs) have been related to multiple cancers, including breast cancer, hepatocellular cancer, lung cancer and colorectal cancer. ERK1/2 inhibitor can suppress growth of KRAS

    Authors: Zilong Yan, Kenoki Ohuchida, Shuang Fei, Biao Zheng, Weiyu Guan, Haimin Feng, Shin Kibe, Yohei Ando, Kazuhiro Koikawa, Toshiya Abe, Chika Iwamoto, Koji Shindo, Taiki Moriyama, Kohei Nakata, Yoshihiro Miyasaka, Takao Ohtsuka…
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:221
    Content type: Research Published on:

  8. Androgen receptor (AR) is expressed in approximately 70% of breast tumors. Recent studies increasingly support AR as a potential therapeutic target of AR-positive breast cancer. We have previously reported tha...

    Authors: Xiaohong Xia, Chuyi Huang, Yuning Liao, Yuan Liu, Jinchan He, Zhiqiang Guo, Lili Jiang, Xuejun Wang, Jinbao Liu and Hongbiao Huang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:220
    Content type: Research Published on:

  9. Glioblastoma (GBM) is a fatal brain tumor, lacking effective treatment. Epidermal growth factor receptor (EGFR) is recognized as an attractive target for GBM treatment. However, GBMs have very poor responses t...

    Authors: Xuejiao Liu, Xiangyu Chen, Lin Shi, Qianqian Shan, Qiyu Cao, Chenglong Yue, Huan Li, Shengsheng Li, Jie Wang, Shangfeng Gao, Mingshan Niu and Rutong Yu
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:219
    Content type: Research Published on:

  10. Reprogramming of cancer metabolism is a newly recognized hallmark of malignancy. The aberrant glucose metabolism is associated with dramatically increased bioenergetics, biosynthetic, and redox demands, which ...

    Authors: Jinguan Lin, Longzheng Xia, Jiaxin Liang, Yaqian Han, Heran Wang, Linda Oyang, Shiming Tan, Yutong Tian, Shan Rao, Xiaoyan Chen, Yanyan Tang, Min Su, Xia Luo, Ying Wang, Hui Wang, Yujuan Zhou…
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:218
    Content type: Review Published on:

  11. Upregulation of RNA polymerase (Pol) III products, including tRNAs and 5S rRNA, in tumor cells leads to enhanced protein synthesis and tumor formation, making it a potential target for cancer treatment. In thi...

    Authors: Xia Liang, Renxiang Xie, Jinfeng Su, Bingqi Ye, Saisai Wei, Zhibing Liang, Rongpan Bai, Zhanghui Chen, Zhongxiang Li and Xiangwei Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:217
    Content type: Research Published on:

  12. Chronic myeloid leukemia (CML) is a myeloproliferative disease caused by the constitutive tyrosine kinase (TK) activity of the BCR-ABL1 fusion protein. Accordingly, TK inhibitors have drastically changed the d...

    Authors: M. Mancini, S. De Santis, C. Monaldi, L. Bavaro, M. Martelli, F. Castagnetti, G. Gugliotta, G. Rosti, M. A. Santucci, G. Martinelli, M. Cavo and S. Soverini
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:216
    Content type: Research Published on:

  13. The Editor-in-Chief has retracted this article [1] due to concerns about the figures. In Figure 3C, the images from the colony formation assays of all cell lines, excluding the control for the HCCLM9 cell line...

    Authors: Yitao Wang, Xian Qin, Tao Guo, Pengpeng Liu, Ping Wu and Zhisu Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:215
    Content type: Retraction Note Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2017 36:97

  14. Gastric cancer is one of the deadliest malignant tumours, with a high incidence in China, and is regulated by aberrantly overexpressed oncogenes. However, existing therapies are insufficient to meet patients’ ...

    Authors: Xiao-Xin Zhang, Bo Ni, Qing Li, Li-Peng Hu, Shu-Heng Jiang, Rong-Kun Li, Guang-Ang Tian, Li-Li Zhu, Jun Li, Xue-Li Zhang, Yan-Li Zhang, Xiao-Mei Yang, Qin Yang, Ya-Hui Wang, Chun-Chao Zhu and Zhi-Gang Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:214
    Content type: Research Published on:

  15. High expression of secreted matricellular protein cysteine-rich 61 (CYR61) correlates with poor prognosis in colorectal cancer (CRC). Aberrant enhancer activation has been shown to correlate with expression of ke...

    Authors: Lingzhu Xie, Xuhong Song, Hao Lin, Zikai Chen, Qidong Li, Tangfei Guo, Tian Xu, Ting Su, Man Xu, Xiaolan Chang, Long-Kun Wang, Bin Liang and Dongyang Huang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:213
    Content type: Research Published on:

  16. Mucosal melanoma with poor prognosis is a common histopathologic subtype of melanoma among Chinese and other Asian peoples. Regulated microRNAs (miRNAs) have been reported as oncogenes or tumour suppressors in...

    Authors: Huan Tang, Meng Ma, Jie Dai, Chuanliang Cui, Lu Si, Xinan Sheng, Zhihong Chi, Longwen Xu, Sifan Yu, Tianxiao Xu, Junya Yan, Huan Yu, Lu Yang, Yan Kong and Jun Guo
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:212
    Content type: Research Published on:

  17. Epidermal growth factor receptor (EGFR) and epidermal growth factor receptor pathway substrate 8 (Eps8) have been widely reported to be expressed in various tumors. Eps8 is an important active kinase substrate...

    Authors: Meifang Li, Jilong Yang, Lenghe Zhang, Sanfang Tu, Xuan Zhou, Ze Tan, Weijun Zhou, Yanjie He and Yuhua Li
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:211
    Content type: Research Published on:

  18. Metformin, a biguanide, is one of the most commonly prescribed treatments for type 2 diabetes and has recently been recommended as a potential drug candidate for advanced cancer therapy. Although Metformin has...

    Authors: Shaymaa IK. Al-Juboori, Jayakumar Vadakekolathu, Sarra Idri, Sarah Wagner, Dimitrios Zafeiris, Joshua RD. Pearson, Rukaia Almshayakhchi, Michele Caraglia, Vincenzo Desiderio, Amanda K. Miles, David J. Boocock, Graham R. Ball and Tarik Regad
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:210
    Content type: Research Published on:

  19. Growing preclinical evidence shows that short-term fasting (STF) protects from toxicity while enhancing the efficacy of a variety of chemotherapeutic agents in the treatment of various tumour types. STF reinfo...

    Authors: Stefanie de Groot, Hanno Pijl, Jacobus J. M. van der Hoeven and Judith R. Kroep
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:209
    Content type: Review Published on:

  20. Thyroid carcinoma includes several variants characterized by different biological and clinical features: from indolent microcarcinoma to undifferentiated and aggressive anaplastic carcinoma. Inflammation plays...

    Authors: Mara Mazzoni, Giuseppe Mauro, Marco Erreni, Paola Romeo, Emanuela Minna, Maria Grazia Vizioli, Cristina Belgiovine, Maria Grazia Rizzetti, Sonia Pagliardini, Roberta Avigni, Maria Chiara Anania, Paola Allavena, Maria Grazia Borrello and Angela Greco
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:208
    Content type: Research Published on:

  21. Cisplatin is one of the most widely used chemotherapeutic agents, but its efficacy is limited by its side effects. Hence, it is of great significance to develop novel agents to synergize with cisplatin and dec...

    Authors: Wei He, Yiqun Xia, Peihai Cao, Lin Hong, Tingting Zhang, Xin Shen, Peisen Zheng, Huanpei Shen, Guang Liang and Peng Zou
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:207
    Content type: Research Published on:

  22. The aberrant expression of myotubularin-related protein 2 (MTMR2) has been found in some cancers, but little is known about the roles and clinical relevance. The present study aimed to investigate the roles an...

    Authors: Lei Jiang, Jun-yan Liu, Yan Shi, Bo Tang, Tao He, Jia-jia Liu, Jun-yan Fan, Bin Wu, Xian-hui Xu, Yong-liang Zhao, Feng Qian, You-hong Cui and Pei-wu Yu
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:206
    Content type: Research Published on:

  23. The aim of this study is to explore the molecular mechanism of the LIM protein Ajuba and the transcription factor SP1 in the pathogenesis and progression of PDAC. Ajuba is a newly defined transcriptional co-re...

    Authors: Bosen Zhang, Liwei Song, Jiali Cai, Lei Li, Hong Xu, Mengying Li, Jiamin Wang, Minmin Shi, Hao Chen, Hao Jia and Zhaoyuan Hou
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:205
    Content type: Research Published on:

  24. The treatment for advanced primary hepatocellular carcinoma (HCC) is sorafenib (SORA), while HCC has become increasingly drug resistant with enhanced aerobic glycolysis. The present study aimed to examine the ...

    Authors: Jiao Feng, Liwei Wu, Jie Ji, Kan Chen, Qiang Yu, Jie Zhang, Jiaojiao Chen, Yuqing Mao, Fan Wang, Weiqi Dai, Ling Xu, Jianye Wu and Chuanyong Guo
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:204
    Content type: Research Published on:

  25. The VRK1 chromatin kinase regulates the organization of locally altered chromatin induced by DNA damage. The combination of ionizing radiation with inhibitors of DNA damage responses increases the accumulation...

    Authors: Ignacio Campillo-Marcos and Pedro A. Lazo
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:203
    Content type: Research Published on:

  26. Glioblastoma multiforme (GBM), due to its location, aggressiveness, heterogeneity and infiltrative growth, is characterized by an exceptionally dismal clinical outcome. The small molecule SI113, recently ident...

    Authors: Silvia Matteoni, Claudia Abbruzzese, Paola Matarrese, Gabriele De Luca, Anna M. Mileo, Stefania Miccadei, Silvia Schenone, Francesca Musumeci, Tobias L. Haas, Giovanni Sette, Carmine M. Carapella, Rosario Amato, Nicola Perrotti, Michele Signore and Marco G. Paggi
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:202
    Content type: Research Published on:

  27. Cancer stem cells (CSCs), which are involved in cancer initiation and metastasis, could potentially release exosomes that mediate cellular communication by delivering microRNAs (miRNAs). Based on the role of m...

    Authors: Zhi-Fei Wang, Fan Liao, Hao Wu and Jin Dai
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:201
    Content type: Research Published on:

  28. Acute myeloid leukemia (AML) is initiated and maintained by a unique, small subset of leukemia stem cells (LSCs). LSCs are characterized by unrestricted self-renewal and contribute to the malignancy of leukemi...

    Authors: Bing Liu, Hongye Ma, Qianqian Liu, Yang Xiao, Shimeng Pan, Huimin Zhou and Li Jia
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:200
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2023 42:208

  29. Noncoding RNAs, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are becoming key parts in the development of multidrug resistance (MDR) in T-cell acute lymphoblastic leukemia (T-ALL). Abnormal ...

    Authors: Qianqian Liu, Hongye Ma, Xiuhua Sun, Bing Liu, Yang Xiao, Shimeng Pan, Huimin Zhou, Weijie Dong and Li Jia
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:199
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2019 38:357

  30. Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. O...

    Authors: Haoming Mai, Bin Zhou, Li Liu, Fu Yang, Carly Conran, Yuan Ji, Jinlin Hou and Deke Jiang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:198
    Content type: Review Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2019 38:352

  31. Cancer pain is a debilitating disorder of human breast cancer and a primary determinant of the poor quality of life, and relieving pain is fundamental strategy in the cancer treatment. However, opioid analgesi...

    Authors: Jiachuan Yu, Yuanyuan Luo and Qingping Wen
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:197
    Content type: Research Published on:

  32. Deregulation of protein translation control is a hallmark of cancers. Eukaryotic initiation factor 4A2 (EIF4A2) is required for mRNA binding to ribosome and plays an important role in translation initiation. H...

    Authors: Zhan-Hong Chen, Jing-Jing Qi, Qi-Nian Wu, Jia-Huan Lu, Ze-Xian Liu, Yun Wang, Pei-Shan Hu, Ting Li, Jin-Fei Lin, Xiang-Yuan Wu, Lei Miao, Zhao-Lei Zeng, Dan Xie, Huai-Qiang Ju, Rui-Hua Xu and Feng Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:196
    Content type: Research Published on:

  33. Triple negative breast cancer (TNBC), which is typically lack of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), represents the most aggre...

    Authors: Jiang-Jiang Qin, Li Yan, Jia Zhang and Wei-Dong Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:195
    Content type: Review Published on:

  34. Accumulating evidence has highlighted the potential role of long non-coding RNAs (lncRNAs) in the biological behaviors of hepatocellular carcinoma (HCC). Here, we elucidated the function and possible molecular...

    Authors: Zhikui Liu, Yufeng Wang, Liang Wang, Bowen Yao, Liankang Sun, Runkun Liu, Tianxiang Chen, Yongshen Niu, Kangsheng Tu and Qingguang Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:194
    Content type: Research Published on:

  35. Several targeted immunotherapies have recently showed significant advances in treatment of non-small cell lung cancer (NSCLC), including antibodies and inhibitors targeting programmed death-1 (PD-1) and its li...

    Authors: Yanhui Chen, Quanxing Liu, Zhiming Chen, Yating Wang, Wanning Yang, Ying Hu, Wenbo Han, Hui Zeng, Haitao Ma, Jigang Dai and Henghui Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:193
    Content type: Research Published on:

  36. Modulation of cell surface expression of MHC class I chain-related protein A/B (MICA/B) has been proven to be one of the mechanisms by which tumor cells escape from NK cell-mediated killing. Abnormal metabolic...

    Authors: Qingke Duan, Hehe Li, Chenggang Gao, Hengqiang Zhao, Shihong Wu, Heshui Wu, Chunyou Wang, Qiang Shen and Tao Yin
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:192
    Content type: Research Published on:

  37. The very aggressive nature and low survival rate of pancreatic ductal adenocarcinoma (PDAC) dictates the necessity to find novel efficacious therapies. Recent evidence suggests that phosphoinositide 3-kinase (...

    Authors: Aikaterini Emmanouilidi, Chanse A. Fyffe, Riccardo Ferro, Charlotte E. Edling, Emily Capone, Simona Sestito, Simona Rapposelli, Rossano Lattanzio, Stefano Iacobelli, Gianluca Sala, Tania Maffucci and Marco Falasca
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:191
    Content type: Research Published on:

  38. One of the most potent costimulatory molecules involved in the recognition and killing of tumor cells is CD80. However, its role and the molecular mechanisms regulating its expression in sporadic colorectal ca...

    Authors: Chiara Marchiori, Melania Scarpa, Andromachi Kotsafti, Susan Morgan, Matteo Fassan, Vincenza Guzzardo, Andrea Porzionato, Imerio Angriman, Cesare Ruffolo, Stefania Sut, Stefano Dall’Acqua, Romeo Bardini, Raffaele De Caro, Carlo Castoro, Marco Scarpa and Ignazio Castagliuolo
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:190
    Content type: Research Published on:

  39. Hepatocellular carcinoma (HCC) is still the most common cause of tumor-related death worldwide and accumulating studies report that long non-coding RNAs (LncRNAs) are closely related with HCC development, meta...

    Authors: Hongda Ding, Junpeng Liu, Ruoyao Zou, Pengrui Cheng and Yang Su
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:189
    Content type: Research Published on:

  40. Forkhead box M1 (FOXM1) is a proliferation-associated transcription factor of the forkhead box proteins superfamily, which includes four isoforms FOXM1a, b, c, and d. FOXM1 has been implicated in hepatocellula...

    Authors: Guohui Hu, Zhengwei Yan, Cheng Zhang, Minzhang Cheng, Yehong Yan, Yiting Wang, Libin Deng, Quqin Lu and Shiwen Luo
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:188
    Content type: Research Published on:

  41. Current prognostic tools and targeted therapeutic approaches have limited value for metastatic triple negative breast cancer (TNBC). Building upon current knowledge, we hypothesized that epoxyeicosatrienoic ac...

    Authors: Maria Karmella Apaya, Jeng-Yuan Shiau, Guo-Shiou Liao, Yu-Jen Liang, Chia-Wei Chen, Hsin-Chou Yang, Chi-Hong Chu, Jyh-Cherng Yu and Lie-Fen Shyur
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:187
    Content type: Research Published on:

  42. Breast cancer is the most prevalent cancer among women. In triple-negative breast cancer (TNBC) cells, a novel quinone derivative, coenzyme Q0 (CoQ0), promotes apoptosis and cell-cycle arrest. This study explored...

    Authors: Hsin-Ling Yang, Varadharajan Thiyagarajan, Pei-Chun Shen, Dony Chacko Mathew, Kai-Yuan Lin, Jiunn-Wang Liao and You-Cheng Hseu
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:186
    Content type: Research Published on:

  43. Malignant peripheral nerve sheath tumours (MPNSTs) are sarcomas of Schwann cell lineage origin that occur sporadically or in association with the inherited syndrome, neurofibromatosis type 1 (NF1). This study ...

    Authors: Kang Yang, Wei Guo, Tingting Ren, Yi Huang, Yu Han, Hongliang Zhang and Jie Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:185
    Content type: Research Published on:

  44. Celastrol, a triterpene compound derived from the traditional Chinese medicine Tripterygium wilfordii, has been reported to possess potential antitumor activity towards various malignancies. However, the effect o...

    Authors: Xihong Liu, Peiyuan Zhao, Xiujuan Wang, Lei Wang, Yingjun Zhu, Yadi Song and Wei Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:184
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2019 38:284

  45. Acquired resistance to sorafenib greatly limits its therapeutic efficiency in the treatment of hepatocellular carcinoma (HCC). Increasing evidence indicates that long noncoding RNAs (lncRNAs) play important ro...

    Authors: Weidong Li, Xuesong Dong, Changjun He, Gang Tan, Ziyi Li, Bo Zhai, Jing Feng, Xian Jiang, Chang Liu, Hongchi Jiang and Xueying Sun
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:183
    Content type: Research Published on:

  46. MicroRNA-139-5p (miR-139) has been shown to play important roles in hepatocellular carcinoma (HCC) development. However, the exact mechanism of miR-139 in HCC remains largely unknown.

    Authors: Ying Zan, Baofeng Wang, Liang Liang, Yujiao Deng, Tian Tian, Zhijun Dai and Lei Dong
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:182
    Content type: Research Published on:

  47. GMEB1 was originally identified via its interaction with GMEB2, which binds to the promoter region of the tyrosine aminotransferase (TAT) gene and modulates transactivation of the glucocorticoid receptor gene. In...

    Authors: Wentao An, Shun Yao, Xiaoyang Sun, Zhaoyuan Hou, Yidan Lin, Ling Su and Xiangguo Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:181
    Content type: Research Published on:

  48. Lung cancer often ranks one of the most prevalent malignancies in the world. One of the most challenging aspects of treating late-stage lung cancer patients is the development of drug resistance, from both con...

    Authors: Wen-Chien Huang, Kuang-Tai Kuo, Chun-Hua Wang, Chi-Tai Yeh and Yongjie Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:180
    Content type: Research Published on:

  49. Recent studies have revealed that numerous oncogenic long non-coding RNAs (lncRNAs) play pivotal roles in pancreatic ductal adenocarcinoma (PDAC) progression, but little is known about tumor-suppressive lncRNA...

    Authors: Jing Ling, Fan Wang, Chuan Liu, Xiao Dong, Ying Xue, Xuebing Jia, Weifeng Song and Qi Li
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:179
    Content type: Research Published on:

  50. .

    Authors: Sen Li, Xiliang Cong, Hongyu Gao, Xiuwen Lan, Zhiguo Li, Wenpeng Wang, Shubin Song, Yimin Wang, Chunfeng Li, Hongfeng Zhang, Yuzhou Zhao and Yingwei Xue
    Citation: Journal of Experimental & Clinical Cancer Research 2019 38:177
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2019 38:6

Annual Journal Metrics

  • 2022 Citation Impact
    11.3 - 2-year Impact Factor
    11.5 - 5-year Impact Factor
    1.870 - SNIP (Source Normalized Impact per Paper)
    2.413 - SJR (SCImago Journal Rank)

    2023 Speed
    4 days submission to first editorial decision for all manuscripts (Median)
    100 days submission to accept (Median)

    2023 Usage 
    3,003,080 downloads
    3,022 Altmetric mentions

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us