Skip to main content

Articles

Page 45 of 76

  1. Colorectal cancer (CRC) is one of the most prevalent malignancies in the world and developed drug resistance has represented one of the most challenging tasks for management. The current therapeutic regimens m...

    Authors: Mao-Hua Cai, Xiao-Gang Xu, Shi-Li Yan, Ze Sun, Yin Ying, Bai-Kui Wang and Yue-Xing Tu
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:151
    Content type: Research Published on:

  2. The natural history of mantle cell lymphoma (MCL) is a continuous process with the vicious cycle of remission and recurrence. Because MCL cells are most vulnerable before their exposure to therapeutic agents, ...

    Authors: Haige Ye, Aakash Desai, Shengjian Huang, Dayoung Jung, Richard Champlin, Dongfeng Zeng, Fangfang Yan, Krystle Nomie, Jorge Romaguera, Makhdum Ahmed and Michael L. Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:150
    Content type: Review Published on:

  3. The long non-coding RNAs (lncRNAs) have participated in the promotion of hepatocellular carcinoma (HCC) initiation and progression. Nevertheless, the biological role and underlying mechanism of LINC01287 in HC...

    Authors: Yichao Mo, Longguang He, Zeru Lai, Zhiheng Wan, Qinshou Chen, Sibo Pan, Liangfu Li, Dasheng Li, Junwei Huang, Fan Xue and Siyao Che
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:149
    Content type: Research Published on:

  4. Exosomes are small vesicles containing a wide range of functional proteins, mRNA and miRNA. Exosomal miRNAs from cancer cells play crucial roles in mediating cell-cell communication and tumor-microenvironment ...

    Authors: Juan Lu, Qi-Hui Liu, Fan Wang, Jia-Jie Tan, Yue-Qin Deng, Xiao-Hong Peng, Xiong Liu, Bao Zhang, Xia Xu and Xiang-Ping Li
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:147
    Content type: Research Published on:

  5. The disruption of E-cadherin-mediated adhesion is considered an important driver of tumor progression. Nevertheless, numerous studies have demonstrated that E-cadherin promotes growth- or invasion-related sign...

    Authors: Katia Rea, Francesca Roggiani, Loris De Cecco, Francesco Raspagliesi, Maria Luisa Carcangiu, Joyce Nair-Menon, Marina Bagnoli, Ileana Bortolomai, Delia Mezzanzanica, Silvana Canevari, Antonis Kourtidis, Panos Z. Anastasiadis and Antonella Tomassetti
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:146
    Content type: Research Published on:

  6. Next-generation sequencing of the exome and genome of prostate cancers has identified numerous genetic alterations. SPOP (Speckle-type POZ Protein) is one of the most frequently mutated genes in primary prostate ...

    Authors: Jian Ma, Kun Chang, Jingtao Peng, Qing Shi, Hualei Gan, Kun Gao, Kai Feng, Fujiang Xu, Hailiang Zhang, Bo Dai, Yao Zhu, Guohai Shi, Yijun Shen, Yiping Zhu, Xiaojian Qin, Yao Li…
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:145
    Content type: Research Published on:

  7. Serine/threonine protein kinase 25 (STK25) is critical in regulating whole-body glucose and insulin homeostasis and the accumulation of ectopic lipids. The Warburg effect, also known as aerobic glycolysis, is ...

    Authors: Fan Wu, Pin Gao, Wei Wu, Zaozao Wang, Jie Yang, Jiabo Di, Beihai Jiang and Xiangqian Su
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:144
    Content type: Research Published on:

  8. Treatment strategies targeting tumor-associated macrophages (TAMs) have been proposed in cancer areas. The functional alterations of macrophages in the microenvironment during the tumorigenesis of human epithe...

    Authors: Meng Xiao, Jianjun Zhang, Wanjun Chen and Wantao Chen
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:143
    Content type: Research Published on:

  9. JS-K is a nitric oxide (NO) donor and could generate intracellularly high levels of NO. The study explores PP2A as a tumor suppressor is a major determinant mediating JS-K-caused apoptosis in human hepatocellu...

    Authors: Ling Liu, Zile Huang, Jingjing Chen, Jiangang Wang and Shuying Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:142
    Content type: Research Published on:

  10. Metastasis is the leading cause of cancer mortality and is a major hurdle for lung cancer treatment. Invadopodia, which are cancer-specific protrusive structures, play a crucial role in the metastatic cascade ...

    Authors: Yongwen Li, Hongbing Zhang, Hao Gong, Yin Yuan, Ying Li, Cong Wang, Weiting Li, Zihe Zhang, Minghui Liu, Hongyu Liu and Jun Chen
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:141
    Content type: Research Published on:

  11. Mounting evidence suggests that RAF-mediated MEK activation plays a crucial role in paradox MAPK (re)activation, leading to resistance and therapeutic failure with agents hitting a single step along the MAPK c...

    Authors: Anais Del Curatolo, Fabiana Conciatori, Ursula Cesta Incani, Chiara Bazzichetto, Italia Falcone, Vincenzo Corbo, Sabrina D’Agosto, Adriana Eramo, Giovanni Sette, Isabella Sperduti, Teresa De Luca, Mirko Marabese, Senji Shirasawa, Ruggero De Maria, Aldo Scarpa, Massimo Broggini…
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:140
    Content type: Research Published on:

  12. Patients with endometrial cancer (EC) and presumably with good prognosis may develop a recurrence indicating that the classification of this tumor is still not definitive and that new markers are needed to ide...

    Authors: Giacomo Corrado, Valentina Laquintana, Rossella Loria, Mariantonia Carosi, Laura de Salvo, Isabella Sperduti, Ashanti Zampa, Lucia Cicchillitti, Giulia Piaggio, Giuseppe Cutillo, Rita Falcioni and Enrico Vizza
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:139
    Content type: Research Published on:

  13. Melanoma is a malignant tumor with high misdiagnosis rate and poor prognosis. The bio-targeted therapy is a prevailing method in the treatment of melanoma; however, the accompanying drug resistance is inevitab...

    Authors: An-dong Liu, Hui Xu, Ya-nan Gao, Dan-ni Luo, Zhao-feng Li, Courtney Voss, Shawn S. C. Li and Xuan Cao
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:138
    Content type: Research Published on:

  14. The immune system is composed of immune as well as non-immune cells. As this system is a well-established component of human papillomavirus- (HPV)-related carcinogenesis, high risk human papillomavirus (hrHPV)...

    Authors: Marconi Rego Barros Jr, Cristiane Moutinho Lagos de Melo, Maria Luiza Carneiro Moura Gonçalves Rego Barros, Rita de Cássia Pereira de Lima, Antonio Carlos de Freitas and Aldo Venuti
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:137
    Content type: Review Published on:

  15. Upregulated fibroblast growth factor 19 (FGF19) expression in human hepatocellular carcinoma (HCC) specimens is associated with tumor progression and poor prognosis. Nonalcoholic steatohepatitis (NASH) patient...

    Authors: Guozhen Cui, Robert C. Martin, Hang Jin, Xingkai Liu, Harshul Pandit, Hengjun Zhao, Lu Cai, Ping Zhang, Wei Li and Yan Li
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:136
    Content type: Research Published on:

  16. Expression of COP9 signalosome subunit 3 (COPS3), an oncogene overexpressed in osteosarcoma, has been demonstrated to be significantly correlated with tumor metastasis. However, the underlying mechanism by whi...

    Authors: Fan Zhang, Taiqiang Yan, Wei Guo, Kunkun Sun, Shidong Wang, Xing Bao, Kuisheng Liu, Bingxin Zheng, Hongliang Zhang and Tingting Ren
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:135
    Content type: Research Published on:

  17. Long non-coding RNAs (lncRNAs) have emerged as important regulators of human cancers. However, the functional roles of lncRNAs and the mechanisms responsible for their aberrant expression in gastric cancer (GC...

    Authors: Xu Zhang, Wei Liang, Jibin Liu, Xueyan Zang, Jianmei Gu, Lei Pan, Hui Shi, Min Fu, Zhenhua Huang, Yu Zhang, Hui Qian, Pengcheng Jiang and Wenrong Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:134
    Content type: Research Published on:

  18. In non-small cell lung cancer (NSCLC), estrogen (E2) significantly promotes NSCLC cell growth via estrogen receptor beta (ERβ). Discovery and elucidation of the mechanism underlying estrogen-promoted NSCLC pro...

    Authors: Quanfu Huang, Zheng Zhang, Yongde Liao, Changyu Liu, Sheng Fan, Xiao Wei, Bo Ai and Jing Xiong
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:133
    Content type: Research Published on:

  19. Glioblastoma (GBM) is the most common, malignant, and lethal primary brain tumor in adults accounting for about 50% of all gliomas. Up to now, the chemotherapy approaches for GBM were limited. 3-O-acetyl-11-ke...

    Authors: Wan Li, Jinyi Liu, Weiqi Fu, Xiangjin Zheng, Liwen Ren, Shiwei Liu, Jinhua Wang, Tengfei Ji and Guanhua Du
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:132
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2022 41:236

  20. Despite advances in diagnosis and treatment, the survival of non-small cell lung cancer (NSCLC) patients remains poor. There is therefore a strong need to identify potential molecular targets for the treatment...

    Authors: Haicheng Tang, Jianjie Zhu, Wenwen Du, Shunlin Liu, Yuanyuan Zeng, Zongli Ding, Yang Zhang, Xueting Wang, Zeyi Liu and Jianan Huang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:131
    Content type: Research Published on:

  21. The aberrant expression of microRNAs (miRNAs) has emerged as important hallmarks of cancer. However, the molecular mechanisms underlying the differences of miRNA expression remain unclear. Many studies have re...

    Authors: Yue Fu, Xinchun Liu, Qiuyang Chen, Tongtai Liu, Cheng Lu, Jun Yu, Yi Miao and Jishu Wei
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:130
    Content type: Research Published on:

  22. Targeting poly ADP-ribose polymerase (PARP) has been recently identified as a promising option against gastric cancer (GC). However, PARP inhibitors alone achieve limited efficacy. Combination strategies, espe...

    Authors: Xiaoting Lin, Dongshao Chen, Cheng Zhang, Xiaotian Zhang, Zhongwu Li, Bin Dong, Jing Gao and Lin Shen
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:129
    Content type: Research Published on:

  23. Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world and metastasis is the leading cause of death associated with HCC. Hypoxia triggers the epithelial-mesenchymal transition (...

    Authors: Xueran Chen, Shangrong Zhang, Zhen Wang, Fengsong Wang, Xinwang Cao, Quan Wu, Chenggang Zhao, Huihui Ma, Fang Ye, Hongzhi Wang and Zhiyou Fang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:128
    Content type: Research Published on:

  24. Circulating tumor cells (CTCs), an advantageous target of liquid biopsy, is an important biomarker for the prognosis and monitoring of cancer. Currently, detection techniques for CTCs are mainly based on the p...

    Authors: Jing Chen, Shunwang Cao, Bo Situ, Juan Zhong, Yanwei Hu, Shufen Li, Jinlan Huang, Jiasen Xu, Shiyang Wu, Jinduan Lin, Qianwen Zhao, Zhen Cai, Lei Zheng and Qian Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:127
    Content type: Research Published on:

  25. The excessive amounts of immunosuppressive factors present in a tumor microenvironment (TME) reduce the effectiveness of cancer vaccines. The main objective of our research was to improve the effectiveness of ...

    Authors: Joanna Rossowska, Natalia Anger, Agnieszka Szczygieł, Jagoda Mierzejewska and Elżbieta Pajtasz-Piasecka
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:126
    Content type: Research Published on:

  26. Oxidative stress is related to ageing and degenerative diseases, including cancer. However, a moderate amount of reactive oxygen species (ROS) is required for the regulation of cellular signalling and gene exp...

    Authors: Rodrigo Prieto-Bermejo, Marta Romo-González, Alejandro Pérez-Fernández, Carla Ijurko and Ángel Hernández-Hernández
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:125
    Content type: Review Published on:

  27. Circulating tumor DNA (ctDNA) and miRNA (ctmiRNA) are promising biomarkers for early tumor diagnosis, prognosis and monitoring, and to predict therapeutic response. However, a clear understanding of the fine c...

    Authors: Jessica Gasparello, Matteo Allegretti, Elisa Tremante, Enrica Fabbri, Carla Azzurra Amoreo, Paolo Romania, Elisa Melucci, Katia Messana, Monica Borgatti, Patrizio Giacomini, Roberto Gambari and Alessia Finotti
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:124
    Content type: Research Published on:

  28. ER-α36, a novel ER-α66 variant, has been demonstrated to promote tamoxifen resistance in breast cancer cells. However, the role and mechanisms of ER-α36 in cisplatin resistance of breast cancer cells remain un...

    Authors: Linlin Zhu, Jiao Zou, Yuanyin Zhao, Xiaomei Jiang, Yang Wang, Xiangwei Wang and Bin Chen
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:123
    Content type: Research Published on:

  29. Serum and glucocorticoid-regulated kinase 3 (SGK3) has been reported to play an important role in tumour progression, but its role in cancer stem cells (CSCs) remains obscure. The phosphoinositide 3-kinase (PI...

    Authors: Fengchao Liu, Xiaoling Wu, Xin Jiang, Yanzhi Qian and Jian Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:122
    Content type: Research Published on:

  30. With self-renewal and differentiation properties, liver tumor initiating cells (TICs) are the reasons for tumor initiation, metastasis and drug resistance. G protein coupled receptors (GPCR) are critical modul...

    Authors: Guanqun Huang, Hui Jiang, Ye Lin, Wuzheng Xia, Yuanwei Luo, Yanpeng Wu, Weilong Cai, Xinke Zhou and Xianhan Jiang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:121
    Content type: Research Published on:

  31. Long non-coding RNAs (lncRNAs) refer to functional cellular RNAs molecules longer than 200 nucleotides in length. Unlike microRNAs, which have been widely studied, little is known about the enigmatic role of l...

    Authors: Lei Zhan, Jun Li and Bing Wei
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:120
    Content type: Review Published on:

  32. Oncogenes derived from the neurotrophin receptor tropomyosin-related kinase TrkA act as drivers in sub-populations of a wide-range of human cancers. This, combined with a recent report that both adult and chil...

    Authors: Antonietta Rosella Farina, Lucia Cappabianca, Pierdomenico Ruggeri, Luciana Gneo, Cristina Pellegrini, Maria-Concetta Fargnoli and Andrew Reay Mackay
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:119
    Content type: Review Published on:

  33. Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the bulk of tumor cells, CSCs or TICs are refrac...

    Authors: Mei Yi, Junjun Li, Shengnan Chen, Jing Cai, Yuanyuan Ban, Qian Peng, Ying Zhou, Zhaoyang Zeng, Shuping Peng, Xiaoling Li, Wei Xiong, Guiyuan Li and Bo Xiang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:118
    Content type: Review Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2018 37:155

  34. Increasing evidence reveals a significant correlation between gamma-synuclein (SNCG) level and tumor invasion and metastasis in various human cancers. Our previous investigation showed that SNCG could secrete ...

    Authors: Caiyun Liu, Like Qu, Chuanke Zhao and Chengchao Shou
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:117
    Content type: Research Published on:

  35. Many tripartite motif (TRIM) family proteins have been reported to be of great importance in the initiation and progression in hepatocellular carcinoma (HCC). However, the biological role and regulatory mechan...

    Authors: Yi Zhang, Ran Tao, Shan-Shan Wu, Cui-Cui Xu, Jie-Ling Wang, Jie Chen, Yong-Sheng Yu, Zheng-Hao Tang, Xiao-Hua Chen and Guo-Qing Zang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:116
    Content type: Research Published on:

  36. To test the hypothesis that activated extracellular signal-regulated kinase (ERK) regulates P65-miR23a/27a/24 axis in gastric cancer (GC) and the ERK-P65-miR23a/27a/24 axis plays an important role in the devel...

    Authors: Li-Dong Zu, Xing-Chun Peng, Zhi Zeng, Jing-Long Wang, Li-Li Meng, Wei-Wei Shen, Chun-Ting Hu, Ye Yang and Guo-Hui Fu
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:115
    Content type: Research Published on:

  37. Tetrandrine, a bisbenzylisoquinoline alkaloid that was isolated from the medicinal plant Stephania tetrandrine S. Moore, was recently identified as a novel chemotherapy drug. Tetrandrine exhibited a potential ant...

    Authors: Man Yu, Ting Liu, Yicheng Chen, Yafang Li and Wenhua Li
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:114
    Content type: Research Published on:

  38. Angiogenesis is considered as an important process in the development of malignancies and is associated with cancer progression and metastasis. Hepatocellular carcinoma (HCC) is the most common primary tumor o...

    Authors: Jinduan Lin, Shunwang Cao, Yu Wang, Yanwei Hu, Hongwei Liu, Jiehua Li, Jing Chen, Pan Li, Jumei Liu, Qian Wang and Lei Zheng
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:113
    Content type: Research Published on:

  39. In the publication of this article [1], there is an error in Fig. 7. The minus and plus signals are inverted which impairs understanding of the results described.

    Authors: Duarte Mendes Oliveira, Katia Grillone, Chiara Mignogna, Valentina De Falco, Carmelo Laudanna, Flavia Biamonte, Rosa Locane, Francesco Corcione, Massimiliano Fabozzi, Rosario Sacco, Giuseppe Viglietto, Donatella Malanga and Antonia Rizzuto
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:112
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2018 37:84

  40. The expression of desmosomal genes in lung adenocarcinoma and lung squamous carcinoma is different. However, the regulatory mechanism of desmosomal gene expression in lung adenocarcinoma and lung squamous carc...

    Authors: Xianglin Hao, Fei Han, Bangjin Ma, Ning Zhang, Hongqiang Chen, Xiao Jiang, Li Yin, Wenbin Liu, Lin Ao, Jia Cao and Jinyi Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:111
    Content type: Research Published on:

  41. Immune checkpoints include stimulatory and inhibitory checkpoint molecules. In recent years, inhibitory checkpoints, including cytotoxic T lymphocyte–associated antigen 4 (CTLA-4), programmed cell death protei...

    Authors: Feng Xu, Tianqiang Jin, Yuwen Zhu and Chaoliu Dai
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:110
    Content type: Review Published on:

  42. Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide and has poor prognosis. Specially, patients with HCC usually have poor tolerance of systemic chemotherapy, because HCCs devel...

    Authors: Yeonhwa Song, Jin-Sun Kim, Se-Hyuk Kim, Yoon Kyung Park, Eunsil Yu, Ki-Hun Kim, Eul-Ju Seo, Heung-Bum Oh, Han Chu Lee, Kang Mo Kim and Haeng Ran Seo
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:109
    Content type: Research Published on:

  43. In the publication of this article [1], there was an error in Figs. 2, 3 and 6.

    Authors: Bao-Xia Li, Heng-Bang Wang, Miao-Zhen Qiu, Qiu-Yun Luo, Han-Jie Yi, Xiang-Lei Yan, Wen-Tao Pan, Lu-Ping Yuan, Yu-Xin Zhang, Jian-Hua Xu, Lin Zhang and Da-Jun Yang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:108
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2018 37:53

  44. PARP1 facilitates the recovery of DNA-damaged cells by recruiting DNA damage response molecules such as γH2AX and BRCA1/2, and plays a role in resistance to antitumor therapies. Therefore, PARP inhibition bein...

    Authors: Hye Jeong Park, Jun Sang Bae, Kyoung Min Kim, Young Jae Moon, See-Hyoung Park, Sang Hoon Ha, Usama Khamis Hussein, Zhongkai Zhang, Ho Sung Park, Byung-Hyun Park, Woo Sung Moon, Jung Ryul Kim and Kyu Yun Jang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:107
    Content type: Research Published on:

  45. LncRNA TUG1 has been reported to be highly expressed in CRC samples and cells and promoted metastasis by affecting EMT, indicating a poor prognosis for colorectal cancer (CRC). In this study, we determined the...

    Authors: Junfeng Sun, Jiyi Hu, Guojun Wang, Zhen Yang, Chunlin Zhao, Xiefu Zhang and Jiaxiang Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:106
    Content type: Research Published on:

    The Retraction Note to this article has been published in Journal of Experimental & Clinical Cancer Research 2021 40:55

  46. Liver tumor initiating cells (TICs) have self-renewal and differentiate capacities, and largely contribute to tumor initiation, metastasis and drug resistance. MAPK signaling is a critical pathway in many biol...

    Authors: Guanqun Huang, Hui Jiang, Yueming He, Ye Lin, Wuzheng Xia, Yuanwei Luo, Min Liang, Boyun Shi, Xinke Zhou and Zhixiang Jian
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:105
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2019 38:500

  47. Great progress has been achieved in the study of the aerobic glycolysis or the so-called Warburg effect in a variety of cancers; however, the regulation of the Warburg effect in Nasopharyngeal carcinoma (NPC) ...

    Authors: Cheng-fu Cai, Guo-dong Ye, Dong-yan Shen, Wei Zhang, Mao-li Chen, Xin-xin Chen, Da-xiong Han, Yan-jun Mi, Qi-cong Luo, Wang-yu Cai and Shu-yu Yang
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:104
    Content type: Research Published on:

  48. The signal transducer and activator of transcription (STAT) and transforming growth factor-β (TGF-β) signaling pathways play important roles in epithelial ovarian cancer (EOC). However, the mechanism of crosst...

    Authors: Xiaoling Tian, Wencai Guan, Lingyun Zhang, Wenwen Sun, Daibing Zhou, Qunbo Lin, Weimin Ren, Lubna Nadeem and Guoxiong Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:103
    Content type: Research Published on:

  49. Aberrant hypermethylation of cellular genes is a common phenomenon to inactivate genes and promote tumorigenesis in nasopharyngeal carcinoma (NPC).

    Authors: Hsin-Pai Li, Chen-Ching Peng, Chih-Ching Wu, Chien-Hsun Chen, Meng-Jhe Shih, Mei-Yuan Huang, Yi-Ru Lai, Yung-Li Chen, Ting-Wen Chen, Petrus Tang, Yu-Sun Chang, Kai-Ping Chang and Cheng-Lung Hsu
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:102
    Content type: Research Published on:

  50. Spindlin1 (SPIN1), a protein highly expressed in several human cancers, has been correlated with tumorigenesis and development. Alterations of drug metabolizing enzymes and drug transporters are major determin...

    Authors: Xu Chen, Ya-Wen Wang and Peng Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:100
    Content type: Research Published on:

Annual Journal Metrics

  • 2022 Citation Impact
    11.3 - 2-year Impact Factor
    11.5 - 5-year Impact Factor
    1.870 - SNIP (Source Normalized Impact per Paper)
    2.413 - SJR (SCImago Journal Rank)

    2023 Speed
    4 days submission to first editorial decision for all manuscripts (Median)
    100 days submission to accept (Median)

    2023 Usage 
    3,003,080 downloads
    3,022 Altmetric mentions

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us