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Table 4 Prognostic Factors of OS in Multivariate Analysis Using AFT and Cox's Models (n = 206).

From: Prognostic factors of survival time after hematopoietic stem cell transplant in acute lymphoblastic leukemia patients: Cox proportional hazard versus accelerated failure time models

 

Weibull AFT

Cox PH

Cox with time-varying coefficients

Characteristics

Time ratio(95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

Relapse(yes vs. no)

.082(.039 .17)

< .001

5.2(3.1 8.94)

< .001

.69(.25 1.8)

.062

aGVHD(yes vs. no)

.95(.45 2.03)

.91

1.09(.61 1.95)

.76

.96(.53 1.74)

.90

cGVHD(yes vs. no)

1.52(.62 3.72)

.35

.71(.35 1.43)

.34

.16(.04 .62)

.008

Platelet recovery(yes vs. no)

2.37(1.05 5.32)

.037

.52(.28 .96)

.039

.53(.28 1.03)

062

Neutrophil recovery(yes vs. no)

2.71(.62 11.85)

.184

.46(.14 1.44)

.187

.39(.12 1.24)

.12

Ti *cGVHD

    

1.006(1.002 1.011)

.003

Ti *relapse

    

1.012(1.006 1.019)

< .001

Explained variation(R2)

.46

 

.21

 

.34

 
  1. aGVHD; acute graft-versus-host disease, cGVHD; chronic graft-versus-host disease, AFT; accelerated failure time, PH; proportional hazard, HR; hazard ratio, Ti; survival time.
  2. Note: the corresponding regression coefficients in the above models can be obtained by taking logarithm of time ratio and hazard ratio.