Figure 9
Effects of cilengitide in combination with temozolomide on cell adhesion and morphology of glioma cells. Cell lines G28 (left panel) and G44 (right panel) were treated for 24 hours with full medium containing DMSO (A, B), cilengitide at a concentration of 5 μg/ml (C, D), temozolomide (5 μg/ml) (E, F) or cilengitide combined with temozolomide, both at a concentration of 5 μg/ml (G, H) in full medium. Phase contrast micrographs were taken 72 hours after treatment. Results from a representative experiment (of at least 3) are shown.