Table 2 Relationship between Twist expression and clinicopathological findings according to E-cadherin expression
| Â | E-cadherin preserved | P | E-cadherin reduced | P | ||
|---|---|---|---|---|---|---|
Characteristics | Twist high | Twist low | Â | Twist high | Twist low | Â |
| Â | n = 20 (29.9%) | n = 47 (70.2%) | Â | n =50 (50.5%) | n = 49 (49.5%) | Â |
Histology | Â | Â | Â | Â | Â | Â |
   Well | 7 (35.0) | 17 (36.2) | 0.74 | 24 (48.0) | 15 (30.6) | 0.20 |
   Moderate | 10 (50.0) | 26 (55.3) |  | 17 (34.0) | 23 (46.9) |  |
   Poor | 3 (15.0) | 4 (8.5) |  | 9 (18.0) | 11 (22.5) |  |
pT | Â | Â | Â | Â | Â | Â |
   pT1 | 8 (40.0) | 25 (53.2) | 0.28 | 2 (4.0) | 11 (22.5) | 0.027 |
   pT2 | 4 (20.0) | 7 (14.9) |  | 6 (12.0) | 8 (16.3) |  |
   pT3 | 3 (15.0) | 11 (23.4) |  | 31 (62.0) | 22 (44.9) |  |
   pT4 | 5 (25.0) | 4 (8.5) |  | 11 (22.0) | 8 (16.3) |  |
pN | Â | Â | Â | Â | Â | Â |
   pN0 | 10 (50.0) | 34 (72.3) | 0.082 | 11 (22.0) | 10 (20.4) | 0.85 |
   pN1 | 10 (50.0) | 13 (27.7) |  | 39 (78.0) | 39 (79.6) |  |
pM | Â | Â | Â | Â | Â | Â |
   pM0 | 16 (80.0) | 42 (89.4) | 0.32 | 26 (52.0) | 34 (69.4) | 0.076 |
   pM1 | 4 (20.0) | 5 (10.6) |  | 24 (48.0) | 15 (30.6) |  |
pStage | Â | Â | Â | Â | Â | Â |
   I | 7 (35.0) | 19 (40.4) | 0.24 | 0 (0.0) | 4 (8.2) | 0.0022 |
   IIA | 2 (10.0) | 13 (27.7) |  | 8 (16.0) | 6 (12.2) |  |
   IIB | 3 (15.0) | 7 (14.9) |  | 1 (2.0) | 10 (20.4) |  |
   III | 4 (20.0) | 3 (6.4) |  | 17 (34.0) | 14 (28.6) |  |
   IV | 4 (20.0) | 5 (10.6) |  | 24 (48.0) | 15 (30.6) |  |
Lymphatic invasion | Â | Â | Â | Â | Â | Â |
   Positive | 14 (70.0) | 19 (40.4) | 0.025 | 41 (82.0) | 33 (67.4) | 0.092 |
   Negative | 6 (30.0) | 28 (59.6) |  | 9 (18.0) | 16 (32.7) |  |
Venous invasion | Â | Â | Â | Â | Â | Â |
   Positeive | 8 (40.0) | 9 (19.2) | 0.080 | 18 (36.0) | 16 (32.7) | 0.73 |
   Negative | 12 (60.0) | 38 (80.9) |  | 32 (64.0) | 33 (67.4) |  |