Figure 4

Detection of apoptosis by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling staining of tumor tissues. (A) Sections after treatment were stained with the TUNEL analysis to detect apoptotic cells. (B) Apoptotic index was determined by calculating the percentage of apoptotic cells among tumor cells (5 high power fields/slide). The combination group showed the highest apoptotic index. a: Ad-hEndo+ cisplatin; b: Ad-hEndo; c: cisplatin; d: Ad-null; e: NS.