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Table 6 The genotype and allele frequency and odds ratios (OR) of the Arg399Gln polymorphism of XRCC1 gene in patients with head and neck cancer with different tumor size and lymph node status.

From: Genetic polymorphisms in DNA base excision repair gene XRCC1 and the risk of squamous cell carcinoma of the head and neck

 

Tumour size (T)

Node status (N)

Genotype Allele

T3 + T4

Number/Frequency

T1+ T2

Number/Frequency

OR (95% CI)

N1 + N2 + N3

Number/Frequency

N0

Number/Frequency

OR (95% CI)

Arg/Arg

24 (0.40)

13 (0.41)

0,97 (0.41 – 2.34)

8 (0,27)

29 (0.47)

0.41 (0.16 – 1.07)

Arg/Gln

30 (0.50)

14 (0.44)

1.28 (0.54 – 3.05)

17 (0.57)

27 (0.44)

1.70 (0.70 – 4.08)

Gln/Gln

6 (0.10)

5 (0.16)

0.60 (0.17 – 2.14)

5 (0.17)

6 (0.10)

1.86 (0.52 – 6.70)

Arg

78 (0.65)

40 (0.62)

1.11 (0.59 – 2.09)

33 (0.55)

85 (0.69)

0.56 (0.30 – 1.06)

Gln

42 (0.35)

24 (0.38)

0.89 (0.48 – 1.68)

27 (0.45)

39 (0.31)

1.78 (0.94 – 3.36)