Figure 1
HBV and human protein interaction network. (A) Summary of the HBV-human protein (HHBV) interactions. (B) HBV and HHBV interaction network. Red square: HBV protein. Circular node: HHBV. For HBV-HHBV interactions, green lines correspond to activate; blue lines, to inhibit; and red lines, to interact (activate or inhibit unknown), all interaction keywords can be found in Additional file 1, Table S2. For HHBV-HHBV interactions, purple indicates evidence from experiments (High-throughput yeast two-hybrid experiment data was collected from public data sources); light blue, from database (Protein - protein interaction relationship was extracted from KEGG pathway database); and grass green, from literature text mining (Scattered literatures about low throughput research on protein - protein interaction were parsed with an in-house computer program), which derived from the Additional file 1, Table S4.