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Table 3 AMD3100 significantly inhibited MFE and cell number when cocultured with different stromal fibroblasts

From: Breast cancer stromal fibroblasts promote the generation of CD44+CD24- cells through SDF-1/CXCR4 interaction

Culture Condition

MFE (%)

Cell Number (× 105)

Monoculture

1.6 ± 0.1

0.22 ± 0.07

Mammosphere + CAFs

2.3 ± 0.2

0.43 ± 0.14

Mammosphere + NFs

1.5 ± 0.2

0.28 ± 0.08

  1. *P < 0.01 compared with no treatment of AMD3100.