Table 1 List of the most differentially expressed genes whose changes due to DMH treatment could be reversed by folic acid

Downregulated genes

NM_207634

Rps24

ribosomal protein S24 (Rps24), transcript variant 2

0.002356454

2.05154E-06

NM_012052

Rps3

ribosomal protein S3 (Rps3)

0.00933479

6.38113E-06

NM_033073

Krt7

keratin 7

0.024674534

0.001286211

NM_024478

Grpel1

GrpE-like 1, mitochondrial (Grpel1)

0.029123617

3.65271E-05

NM_024243

Fuca1

fucosidase, alpha-L- 1

0.031740456

0.000162318

NM_146050

Oit1

oncoprotein induced transcript 1

0.032247549

0.001799574

NM_013614

Odc1

ornithine decarboxylase, structural 1

0.032361

4.48641E-05

NM_025431

Llph

LLP homolog, long-term synaptic facilitation (Aplysia)

0.036784284

1.18163E-06

NM_008764

Tnfrsf11b

tumor necrosis factor receptor superfamily, member 11b

0.041187965

7.03729E-05

NM_009402

Pglyrp1

peptidoglycan recognition protein 1

0.041272749

0.009299333

NM_010106

Eef1a1

eukaryotic translation elongation factor 1 alpha 1

0.041438052

7.22246E-06

NM_001008700

Il4ra

interleukin 4 receptor, alpha

0.043141894

0.000223171

NM_182930

Plekha6

pleckstrin homology domain containing, family A member 6

0.04544609

0.001545018

NM_011463

Spink4

serine peptidase inhibitor, Kazal type 4

0.045587012

0.000688366

NM_016710

Hmgn5

high-mobility group nucleosome binding domain 5

0.046928235

0.000333311

NM_016981

Slc9a1

solute carrier family 9 (sodium/hydrogen exchanger), member 1

0.052191789

5.29847E-05

NM_145533

Smox

spermine oxidase (Smox), transcript variant 2

0.053274908

6.23127E-05

NM_008305

Hspg2

perlecan (heparan sulfate proteoglycan 2)

0.056450624

0.001205571

NM_172051

Tmcc3

transmembrane and coiled coil domains 3

0.058793481

0.001122075

NM_009768

Bsg

basigin (Bsg), transcript variant 1

0.061259044

0.000407939

Upregulted genes

NM_009946

Cplx2

complexin 2

1109.786672

0.000155322

NM_001039493

Plekhm3

pleckstrin homology domain containing, family M, member 3

56.2494337

0.000450001

NM_024272

Ssbp2

single-stranded DNA binding protein 2 (Ssbp2), transcript variant 2

54.215495

2.06403E-05

NM_175013

Pgm5

phosphoglucomutase 5

47.38198278

1.84156E-05

NM_008222

Hccs

holocytochrome c synthetase

39.34022581

0.000130923

NM_001033364

Cdhr2

cadherin-related family member 2

38.97741927

0.000749154

NM_023566

Muc2

mucin 2

30.63268666

0.02159023

NM_010418

Herc2

hect domain and RCC1 (CHC1)-like domain (RLD) 2

29.34751955

0.003432199

NM_008261

Hnf4a

hepatic nuclear factor 4, alpha

28.66993377

0.000234502

NM_176850

Bptf

bromodomain PHD finger transcription factor

26.66298996

0.000156324