Figure 4

Effects of Flk-1+CD31-CD34- MSCs on T lymphocyte activation. Flk-1+CD31-CD34- MSCs at 1:10 ratios (MSCs to T cells); the data are expressed as mean ± S.D. of triplicates of five separate experiments with similar results. Activators of T cells were analyzed including CD25, CD69, and CD44. The activation of T cells was analyzed in T cells alone (Ts), normal MSC cocultured with activated T cells (BMSC + Ts), and CML-derived MSC cocultured with activated T cells (MDS MSC + Ts). Data are shown as means ± S.D. of five independent experiments (*p ≥ 0.05,**p < 0.05 vs. Ts)