Table 2 Correlation between cancer biomarkers and bone metastasis
Biomarkers | Bone metastasis n (%) | Non-bone metastasis n (%) | P value | |
|---|---|---|---|---|
OPN | + | 40 (93.0) | 48 (77.4) | 0.033 |
- | 3 (7.0) | 14 (22.6) | ||
c-Src | + | 45 (100) | 56 (93.3) | 0.133 |
- | 0 (0) | 4 (6.7) | ||
MMP2 | + | 38 (88.4) | 47 (75.8) | 0.107 |
- | 5 (11.6) | 15 (24.2) | ||
CXCR4 | + | 40 (90.9) | 32 (52.5) | 0.000 |
- | 4 (9.1) | 29 (47.5) | ||
BSP | + | 44 (97.8) | 49 (81.7) | 0.012 |
- | 1 (2.2) | 11 (18.3) | ||
PTHrP | + | 42 (68.8) | 28 (63.4) | 0.647 |
- | 19 (31.2) | 16 (36.6) | ||
IGF-1R | + | 58 (95.1) | 39 (88.6) | 0.383 |
- | 3 (4.9) | 5 (21.4) | ||
BMP4 | + | 22 (48.9) | 51 (85) | 0.000 |
- | 23 (51.1) | 9 (15.0) | ||
PI3K | + | 43 (95.6) | 55 (91.7) | 0.696 |
- | 2 (4.4) | 5 (8.3) | ||
NFκB | + | 58 (95.1) | 39 (88.6) | 0.383 |
- | 3 (4.9) | 5 (21.4) | ||