Figure 5From: The role of estrogen receptor alpha in mediating chemoresistance in breast cancer cellsBcl-2 and Bax protein expression in BC-ER and BC-V cells. BC-ER cells showed lower Bcl-2 expression and higher Bax expression than BC-V cells in the presence of E2 (western blot). Treatment of BC-ER cells with E2 for 12 days downregulated Bcl-2 and upregulated the Bax expression.Back to article page