Parameter | Group | N | Expression of Hsp90-beta | Expression of annexin A1 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Low (%) | Moderate (%) | High (%) | χ2value | P value | Low (%) | Moderate (%) | High (%) | χ2value | P value | |||
Gender | ||||||||||||
Male | 73 | 12(16.4) | 22(30.1) | 39(53.4) | 4.49 | 0.105 | 18(24.7) | 26(35.6) | 29(39.7) | 5.09 | 0.078 | |
Female | 23 | 2(8.7) | 3(13) | 18(78.3) | 2(8.7) | 6(26.1) | 15(65.2) | |||||
Ages | ||||||||||||
<60 | 54 | 8(14.8) | 13(24.1) | 33(61.1) | 0.251 | 0.882 | 8(14.8) | 20(37) | 26(48.1) | 2.798 | 0.247 | |
≥60 | 42 | 6(14.3) | 12(28.6) | 24(57.1) | 12(28.6) | 12(28.6) | 18(42.9) | |||||
Smoking | ||||||||||||
0 | 37 | 3(8.1) | 6(16.2) | 28(75.7) | 8.28 | 0.082 | 5(13.5) | 10(27) | 22(59.5) | 3.856 | 0.248 | |
0.1–40 | 12 | 1(8.33) | 5(41.67) | 6(50) | 2(16.7) | 5(41.7) | 5(41.7) | |||||
>40 | 47 | 10(21.3) | 14(29.8) | 23(48.9) | 13(27.7) | 17(36.2) | 17(36.2) | |||||
Histology | ||||||||||||
LAC | 39 | 8(20.5) | 9(23.1) | 22(56.4)★ | 8.16 | <0.05 | 7(17.9) | 9(23.1) | 23(59)▴ | 7.513 | <0.05 | |
LSCC | 41 | 5(12.2) | 13(31.7) | 23(56.1)★ | 10(24.4) | 19(46.3) | 12(29.3)▴ | |||||
SCLC | 11 | 1(9.1) | 1(9.1) | 9(81.82)★ | 2(18.2) | 2(18.2) | 7(63.6)▴ | |||||
Others | 5 | 0(0) | 2(40) | 3(60) | 1(20) | 2(40) | 2(40) | |||||
Pathological grade | ||||||||||||
Poorly | 26 | 1(3.8) | 4(15.4) | 21(80.8) | 31.26 | <0.0005 | 2(7.7) | 2(7.7) | 22(84.6) | 38.26 | <0.0005 | |
Moderately | 33 | 1(3.03) | 12(36.36) | 20(60.61) | 5(15.2) | 21(63.6) | 7(21.2) | |||||
Well | 22 | 11(50) | 6(27.3) | 5(22.7) | 10(45.5) | 5(22.7) | 7(31.8) | |||||
Undifferentiated | 15 | 1(6.67) | 3(20) | 11(73.33) | 3(20) | 4(26.7) | 8(53.3) | |||||
Lymphatic invasion | ||||||||||||
N0 | 41 | 12(29.3) | 18(43.9) | 11(26.8)★★ | 31.02 | <0.0005 | 17(41.5) | 13(31.7) | 11(26.8)▴▴ | 19.97 | <0.0005 | |
N1 | 40 | 1(2.5) | 5(12.5) | 34(85) ★★ | 2(5.5) | 17(34.5) | 21(60) ▴▴ | |||||
N2 | 11 | 0(0) | 2(18.2) | 9(81.8) ★★ | 1(9.1) | 1(9.1) | 9(81.82)▴▴ | |||||
N3 | 4 | 0(0) | 0(0) | 4(100) ★★ | 0(0) | 0(0) | 4(100) ▴▴ | |||||
hydrothorax | ||||||||||||
Absent | 82 | 13(15.9) | 23(28) | 46(56.1) | 2.51 | 0.285 | 18(22) | 29(35.4) | 35(42.7) | 2.25 | 0.324 | |
Present | 14 | 1(7.1) | 2(14.3) | 11(78.6) | 2(14.3) | 3(21.4) | 9(64.3) | |||||
T stage | ||||||||||||
T1 – T2 | 57 | 11(19.3) | 22(38.6) | 24(42.1) | 14.72 | 0.001 | 17(29.8) | 23(40.4) | 17(29.8) | 14.83 | 0.001 | |
T3 – T4 | 28 | 2(7.1) | 2(7.1) | 24(85.7) | 1(3.6) | 7(25) | 20(71.4) | |||||
Unavailable | 11 | 1(9.1) | 1(9.1) | 9(81.82) | 2(18.18) | 2(18.18) | 7(63.64) | |||||
pTNM | ||||||||||||
IB | 3 | 1(33.3) | 2(66.7) | 0(0)● | 11.449 | 0.022 | 0(0) | 3(100) | 0(0)●● | 9.97 | 0.008 | |
IIA-IIB | 53 | 10(18.9) | 19(35.8) | 24(45.3)● | 16(30.2) | 20(37.7) | 17(32.1)●● | |||||
IIIA-IIIB | 25 | 2(8) | 3(12) | 20(82)● | 2(8) | 6(24) | 17(68)●● | |||||
IV | 4 | 0(0) | 0(0) | 4(100)● | 0(0) | 1(25) | 3(75)●● | |||||
Unavailable | 11 | 1(9.1) | 1(9.1) | 9(81.82) | 2(18.18) | 2(18.18) | 7(63.64) | |||||
Imaging | ||||||||||||
Central | 43 | 5(11.63) | 15(34.88) | 23(53.49) | 2.68 | 0.261 | 11(20.9) | 16(41.9) | 16(37.2) | 2.07 | 0.356 | |
Ambient | 49 | 9(18.37) | 10(24.49) | 30(57.14) | 8(20.4) | 16(32.7) | 25(46.9) | |||||
Unavailable | 4 | 0(0) | 0(0) | 4(100) | 1(25) | 0(0) | 3(75) |