Table 2 Logistic regression analyses on associations between p63 rs873330, p73 rs4648551, rs6695978 and risk of ovarian cancer
Gene and SNP | Genotype of SNP | No. of subjects (%) | Adjusteda | ||
|---|---|---|---|---|---|
Controls | Cases | P | OR (95 % CI) | ||
p63 | |||||
rs873330 T > C | TT | 182 (56.7) | 160 (52.0) | 0.142 | 1.00 (ref) |
TC | 118 (36.8) | 122 (39.6) | Â | 1.15 (0.88-1.52) | |
CC | 21 (6.5) | 26 (8.4) | 1.21 (0.78-1.89) | ||
T allele | 482 (75.1) | 442 (71.8) | Â | ||
C allele | 160 (24.9) | 174 (28.2) | 0.098 | 1.16 (0.79-1.68) | |
p73 | |||||
rs4648551 G > A | GG | 316 (97.5) | 296 (96.1) | 0.936 | 1.00 (ref) |
GA | 8 (2.5) | 10 (3.3) | Â | 1.05 (0.91-1.22) | |
AA | 0 (0.0) | 2 (0.6) | Â | ||
G allele | 640 (98.8) | 602 (97.7) | Â | ||
A allele | 8 (1.2) | 14 (2.3) | 0.558 | 1.41 (0.99-1.93) | |
rs6695978 G > A | GG | 240 (74.1) | 198 (64.3) | 0.004 | 1.00 (ref) |
| Â | GA | 73 (22.5) | 94 (30.5) | Â | 1.64 (1.37-1.95) |
| Â | AA | 11 (3.4) | 16 (5.2) | 1.81 (1.56-2.14) | |
| Â | G allele | 553 (85.3) | 490 (79.5) | Â | |
| Â | A allele | 95 (14.7) | 126 (20.5) | 0.003 | 1.55 (1.07-2.19) |