Figure 5

McAb7E10 induces apoptosis in AML cell lines. (A, B) Annexin V staining and flow cytometry was used to confirm that McAb7E10 induced apoptosis in AML cells. (C) The relative rate of apoptosis in 50 μg/ml McAb7E10 treated MV4-11 cells was 50.5% ± 7.04% vs 21.9% ± 3.11% in mouse IgG treated cells, p < 0.01. (D) The relative rate of apoptosis in 50 μg/ml McAb7E10 treated HL-60 cells was 32.9% ± 4.52% vs 15.3% ± 3.95% in mouse IgG treated cells, p < 0.01.