Table 2 Univariate analyses of the relationships between clinicopathologic factors and survival
From: Expression and prognostic value of VEGFR-2, PDGFR-β, and c-Met in advanced hepatocellular carcinoma
Parameters | N | PFS | OS | |||||
|---|---|---|---|---|---|---|---|---|
Months | χ 2 | P | Months | χ 2 | P | |||
Gender | Male | 55 | 4.433 | 7.400 | ||||
Female | 10 | 6.200 | 0.609 | 0.435 | 10.200 | 0.340 | 0.560 | |
Age | ≤50 | 22 | 4.000 | 5.867 | ||||
>50 | 43 | 5.833 | 3.934 | 0.047 | 8.067 | 0.113 | 0.736 | |
HBsAg | Positive | 55 | 4.433 | 6.467 | ||||
Negative | 10 | 5.833 | 0.516 | 0.472 | 8.800 | 3.608 | 0.057 | |
AFP(IU/ml) | ≤400 | 31 | 7.000 | 11.133 | ||||
>400 | 34 | 4.233 | 3.016 | 0.082 | 5.200 | 5.236 | 0.022 | |
Tumor number | Single | 18 | 5.600 | 8.967 | ||||
>1 | 47 | 4.967 | 0.168 | 0.682 | 5.867 | 0.981 | 0.322 | |
Tumor size(cm) | ≤5 | 12 | 7.300 | 29.267 | ||||
>5 | 53 | 4.367 | 3.792 | 0.051 | 5.867 | 9.834 | 0.002 | |
Differentiation | High | 17 | 6.200 | 5.233 | ||||
Middle | 33 | 4.367 | 8.967 | |||||
Low | 15 | 4.000 | 3.630 | 0.163 | 5.667 | 3.097 | 0.213 | |
Child-Pugh | A | 59 | 5.600 | 8.067 | ||||
B | 6 | 4.967 | 0.599 | 0.439 | 3.600 | 1.980 | 0.159 | |
BCLC | B | 7 | 5.633 | 10.500 | ||||
C | 58 | 4.433 | 3.527 | 0.060 | 7.400 | 0.274 | 0.600 | |
Hepatic cirrhosis | Yes | 34 | 4.967 | 6.533 | ||||
No | 31 | 4.433 | 0.002 | 0.965 | 8.967 | 0.194 | 0.659 | |
Ascites | Yes | 14 | 4.367 | 5.000 | ||||
No | 51 | 5.600 | 2.706 | 0.100 | 8.967 | 3.887 | 0.049 | |
Tumor thrombus | Yes | 28 | 3.000 | 5.000 | ||||
No | 37 | 5.833 | 2.800 | 0.094 | 11.367 | 8.067 | 0.005 | |
Extrahepatic metastasis | Yes | 41 | 4.367 | 6.467 | ||||
No | 24 | 5.600 | 0.878 | 0.349 | 8.967 | 0.017 | 0.897 | |