From: Pharmacokinetic study and evaluation of the safety of taurolidine for dogs with osteosarcoma
Toxicity | Grade I | Circumstances | Grade II | Circumstances |
---|---|---|---|---|
Bone marrow | ||||
Neutropenia | 7 | 1 when T combined with D | 2 | Both when T combined with C |
6 when T combined with C | ||||
Thrombocytopenia | 2 | 1 when T alone | 3 | 2 when T combined with D |
1 when T combined with D | ||||
1 when T combined with C | ||||
Gastrointestinal | ||||
Anorexia | 4 | 2 when T combined with D | 5 | 3 when T combined with D |
1 when T combined with C | 2 when T combined with C | |||
1 when T given by itself one week after C | ||||
Diarrhea | 3 | 2 when T combined with D | 0 | |
1 when T combined with C |