Figure 4From: Comparative examination of various PCR-based methods for DNMT3A and IDH1/2 mutations identification in acute myeloid leukemiaARMS analysis of IDH2 R140Q mutation. 1) Agarose gel analysis of PCR products of 3 positive (97, 107, 122) and 3 negative (94, 114, 126) patients. All patients showed control (613Â bp) and wt (233Â bp) bands, while only the positive patients showed a product at 446Â bp. Hyperladder II (Bioline) was used as the marker. 2) Representative sequence analysis of patient 97 showing the heterozygote mutation CGG to CAG.Back to article page