Table 2 GI 50 s of TAI-1 and commerically available drugs in cell lines
From: Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1
| Â | Cell line | TAI-1 GI50(nM) |
|---|---|---|
Drug resistant cancer cell lines | MEX-SA/Dx5 | 35 |
NCI/ADR-RES | 29 | |
K562R | 30 | |
Normal cell lines | WI-38 | >10 μM |
RPTEC | >10 μM | |
HuVEC | > 9 μM | |
HAoSMC | > 9 μM |