Variable | n | Overall survival rate (%) | Disease-free survival rate (%) | ||||
---|---|---|---|---|---|---|---|
3y | 5y | P value | 3y | 5y | P value | ||
Gender | Â | Â | Â | Â | Â | Â | Â |
 Female | 25 | 87.7 | 66.8 |  | 56.0 | 44.0 |  |
 Male | 87 | 60.9 | 46.4 | 0.100 | 47.1 | 31.8 | 0.234 |
Age (year) | Â | Â | Â | Â | Â | Â | Â |
  ≤ 45 | 29 | 82.4 | 57.3 |  | 62.1 | 37.9 |  |
  > 45 | 83 | 61.4 | 40.8 | 0.417 | 44.6 | 34.7 | 0.639 |
HBsAg statusa | Â | Â | Â | Â | Â | Â | Â |
 Negative | 22 | 90.5 | 85.4 |  | 72.7 | 59.1 |  |
 Positive | 90 | 61.1 | 41.4 | 0.008* | 43.3 | 29.6 | 0.017* |
Cirrhosis | Â | Â | Â | Â | Â | Â | Â |
 No | 37 | 64.2 | 58.1 |  | 51.4 | 39.9 |  |
 Yes | 75 | 68.0 | 47.7 | 0.440 | 48.0 | 33.3 | 0.457 |
AFP (μg/l)b |  |  |  |  |  |  |  |
  ≤ 400 | 55 | 61.3 | 53.4 |  | 49.1 | 39.7 |  |
  > 400 | 57 | 71.9 | 48.7 | 0.699 | 49.1 | 31.6 | 0.714 |
Tumor size | Â | Â | Â | Â | Â | Â | Â |
  ≤ 5 cm | 37 | 75.7 | 58.9 |  | 51.4 | 39.9 |  |
  > 5 cm | 75 | 62.3 | 46.8 | 0.398 | 48.0 | 33.3 | 0.938 |
Tumor number | Â | Â | Â | Â | Â | Â | Â |
 Single | 86 | 71.8 | 57.1 |  | 55.8 | 43.9 |  |
 Multiple | 26 | 50.0 | 30.8 | <0.001* | 26.9 | 7.7 | <0.001* |
Tumor capsule | Â | Â | Â | Â | Â | Â | Â |
 Complete | 20 | 75.0 | 52.2 |  | 50.0 | 44.4 |  |
 Incomplete | 92 | 65.0 | 50.5 | 0.507 | 48.9 | 33.7 | 0.611 |
Vascular invasion | Â | Â | Â | Â | Â | Â | Â |
 No | 86 | 67.2 | 55.0 |  | 53.5 | 41.6 |  |
 Yes | 26 | 65.4 | 37.1 | 0.011* | 34.6 | 15.4 | 0.004* |
Edmondson grade | Â | Â | Â | Â | Â | Â | Â |
 I/II | 64 | 76.3 | 56.0 |  | 64.1 | 44.8 |  |
 III/IV | 48 | 54.2 | 43.7 | 0.027* | 29.2 | 22.9 | 0.002* |
TNM stage | Â | Â | Â | Â | Â | Â | Â |
 I/II | 67 | 69.8 | 62.0 |  | 58.2 | 47.5 |  |
 III/IV | 45 | 62.2 | 34.0 | <0.001* | 35.6 | 17.8 | 0.001* |
DDR2 level | Â | Â | Â | Â | Â | Â | Â |
 Low | 56 | 83.7 | 66.3 |  | 69.6 | 53.1 |  |
 High | 56 | 50.0 | 35.7 | <0.001* | 28.6 | 17.9 | <0.001* |