Fig. 7
From: SYNJ2BP inhibits tumor growth and metastasis by activating DLL4 pathway in hepatocellular carcinoma
Overexpression or silencing of Delta-Like 4 (DLL4) imitates or counteracts Synaptojanin 2 Binding Protein (SYNJ2BP) mediated proliferation and invasion of Hep3B and HCCLM3 cells. DLL4 expression or shDLL4 or control vectors were transfected into previous HCC cells. The MTT (a) and colony formation analysis (b) were used to evaluate the proliferation abilities in Hep3B and HCCLM3 cells. The wound healing assay (c) and transwell assay (d) showed the migration and invasion abilities of Hep3B and HCCLM3 cells. *P < 0.05. NC: Negative Control. Original magnification: 200× for C, 100× for D; pictures from B were captured with the aid of a canon camera