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Table 4 Clinical and pathological characteristics of breast and thyroid cancer patients

From: Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer

Variable

Study population (n = 69)

p53-MCL positive (n = 2)

Age-years

 Average

60.2

58

 Range

30–77

58–63

Age onset Breast tumor appearance

 Average

49.1

48

 Range

25–70

48–51

Breast tumor Diagnosis

 Ductal

59 (85.5 %)

1 (50 %)

 Lobular

3 (4.3 %)

0

 Unknown

7 (10.2 %)

1 (50 %)

ER status

 Negative

17 (24.6 %)

0

 Positive

34 (49.3 %)

2 (100 %)

 Unknown

18 (26.1 %)

0

PgR status

 Negative

17 (24.6 %)

0

 Positive

34 (49.3 %)

2 (100 %)

 Unknown

18 (26.1 %)

0

  1. ER estrogen receptor, PgR progesterone receptor