Skip to main content

Table 1 Combination indexes

From: Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine

 

AZD7762 (nM)

Gemcitabine (nM)

10

20

40

VM-CUB1

 10

0.427

0.239

0.178

 20

0.505

0.408

0.366

RT-112

 10

0.277

0.262

0.232

 20

0.628

0.628

0.645

T24

 10

0.423

0.422

0.369

 20

0.762

0.764

0.751

UM-UC-3

 10

0.495

0.392

0.343

 20

0.725

0.718

0.639

  1. Combination indexes (CI) calculated for the combination of gemcitabine and AZD7762 in urothelial carcinoma cells (CI < 1 indicates synergy)