Fig. 5From: Disulfiram overcomes bortezomib and cytarabine resistance in Down-syndrome-associated acute myeloid leukemia cellsBTZ-resistant cell lines are cross-resistant to CFZ and MG-132 but sensitive to DSF/Cu2+. CMY, CMY BR175, CMY BR200 and CMK BR100 were treated with several concentrations of BTZ, CFZ, MG 132 and DSF/Cu2+ for 72 h, and the dose response curves were plotted. All BTZ-resistant variants were cross-resistant to CFZ and MG-132 but sensitive to DSF/Cu2+ Back to article page