Fig. 4From: Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic miceBuformin regulates AMPK/mTOR and RTK signaling pathways in erbB-2-overexpressing breast cancer cells. SKBR3 and BT474 cells were treated with buformin (0, 0.1, 0.3, 1, or 3Â mM) for 24Â h. Expression and activation/phosphorylation of the indicated proteins relating to the AMPK/mTOR (a) and RTK (b) pathways were analyzed using Western blottingBack to article page