Fig. 5
From: MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression
TMEM16A mediates the effects of miR-381 on migration and invasion in gastric cancer cells. Gastric cancer cells tranfected with agomiR-381 and negative control, together with blank vector or TMEM16A overexpression plasmid. a Western blot analysis showed that ectopic expression of miR-381 reduced the TMEM16A protein expression, while co-transfection of TMEM16A overexpression TMEM16A plasmids could recover the TMEM16A expression. **P < 0.01. b, c Co-transfection of TMEM16A overexpression reverted the suppressive effects of miR-381 overexpression on the migration and invasion of gastric cancer cells**P < 0.01. d, e TMEM16A-overexpressing did not reverse the inhibition of gastric cancer cell proliferation induced by the miR-381 overexpression