[IRS] | BRCA1 mut | sporadic | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
VDR | RXR | PPARγ | VDR | RXR | PPARγ | ||||||||||||||
<4 | ≥4 | p | <4 | ≥4 | p | <4 | ≥4 | p | <4 | ≥4 | p | <4 | ≥4 | p | <4 | ≥4 | p | ||
suptype | other | 3 | 2 | ns | 1 | 4 | ns | 4 | 0 | ns | 2 | 3 | ns | 3 | 3 | ns | 5 | 1 | ns |
NST | 4 | 18 | 9 | 13 | 9 | 7 | 11 | 10 | 8 | 13 | 17 | 4 | |||||||
G | G1-2 | 2 | 5 | ns | 2 | 5 | ns | 4 | 2 | ns | 5 | 2 | ns | 0 | 7 | 0.022 | 7 | 0 | ns |
G3 | 5 | 15 | 8 | 12 | 9 | 5 | 8 | 11 | 11 | 9 | 15 | 5 | |||||||
pT | pT1a-c | 3 | 9 | ns | 3 | 9 | ns | 8 | 2 | ns | 4 | 8 | ns | 5 | 7 | ns | 9 | 3 | ns |
pT2-pT4 | 4 | 11 | 7 | 8 | 5 | 5 | 9 | 5 | 6 | 9 | 13 | 2 | |||||||
pN | pN0 | 2 | 13 | ns | 3 | 12 | ns | 8 | 4 | ns | 6 | 8 | ns | 7 | 8 | ns | 10 | 5 | 0.047 |
pN+ | 5 | 7 | 7 | 5 | 5 | 3 | 7 | 5 | 4 | 8 | 12 | 0 | |||||||
pM | pM0 | 4 | 7 | ns | 3 | 8 | ns | 4 | 3 | ns | 2 | 8 | 0.041 | 3 | 8 | ns | 10 | 1 | ns |
pM+ | 3 | 13 | 7 | 9 | 9 | 4 | 11 | 5 | 8 | 8 | 12 | 4 | |||||||
ER | negative | 6 | 13 | ns | 7 | 12 | ns | 8 | 6 | ns | 8 | 8 | ns | 9 | 8 | ns | 12 | 5 | ns |
positive | 1 | 7 | 3 | 5 | 5 | 1 | 5 | 5 | 2 | 8 | 10 | 0 | |||||||
PR | negative | 4 | 16 | ns | 7 | 13 | ns | 8 | 6 | ns | 9 | 6 | ns | 10 | 6 | 0.008 | 12 | 4 | ns |
positive | 3 | 4 | 3 | 4 | 5 | 1 | 4 | 7 | 1 | 10 | 10 | 1 | |||||||
Her2 | negative | 3 | 13 | ns | 4 | 12 | ns | 8 | 5 | ns | 7 | 4 | ns | 4 | 8 | ns | 9 | 3 | ns |
positive | 1 | 3 | 2 | 2 | 2 | 1 | 2 | 7 | 2 | 7 | 8 | 1 | |||||||
Triple-negative | no | 4 | 9 | ns | 6 | 7 | ns | 9 | 2 | 0.036 | 7 | 10 | ns | 4 | 13 | ns | 16 | 1 | 0.040 |
yes | 0 | 8 | 1 | 7 | 1 | 4 | 4 | 1 | 3 | 3 | 3 | 3 | |||||||
Ki67 | low | 5 | 5 | ns | 6 | 4 | ns | 7 | 3 | ns | 8 | 9 | ns | 8 | 9 | ns | 13 | 4 | ns |
high | 1 | 4 | 1 | 4 | 3 | 1 | 4 | 2 | 3 | 4 | 6 | 1 | |||||||
age | ≤41.5 y | 3 | 9 | ns | 4 | 8 | ns | 3 | 4 | ns | 1 | 3 | ns | 1 | 3 | ns | 4 | 0 | ns |
>41.5 y | 4 | 11 | 6 | 9 | 10 | 3 | 12 | 10 | 10 | 13 | 18 | 5 |