Table 1 Correlations between CTHRC1 levels in ESCC tissues and clinicopathological characteristics of patients with ESCC
Characteristic | Â | CTHRC1 expression | P | |
|---|---|---|---|---|
Low | High | |||
Age | ≤60 | 49 | 67 | 0.128 |
>60 | 28 | 60 | ||
Gender | Male | 62 | 106 | 0.593 |
Female | 15 | 21 | ||
Tobacco use | No | 27 | 45 | 0.957 |
Yes | 50 | 82 | ||
Alcohol use | No | 30 | 46 | 0.695 |
Yes | 47 | 81 | ||
Family history | No | 65 | 106 | 0.858 |
Yes | 12 | 21 | ||
Location | Upper/Middle | 39 | 60 | 0.637 |
Lower | 38 | 67 | ||
Histology grade | G1/G2 | 59 | 94 | 0.677 |
G3 | 18 | 33 | ||
T stage | T1/T2/T3 | 44 | 54 | 0.043 |
T4 | 33 | 73 | ||
Lymph node metastasis | No | 49 | 60 | 0.023 |
Yes | 28 | 67 | ||
TNM stage | I/II | 39 | 44 | 0.024 |
III | 38 | 83 | ||
FRA-1 | Low | 22 | 28 | 0.116 |
High | 45 | 97 | ||
Snail1 | Low | 39 | 53 | 0.100 |
High | 33 | 73 | ||
MMP14 | Low | 45 | 58 | 0.022 |
High | 26 | 67 | ||
Cyclin D1 | Low | 53 | 66 | 0.018 |
High | 24 | 61 | ||