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Table 1 Clinicopathologic correlation of supervillin expression in human HCC

From: Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway

Clinical Pathological Parameters

n

SVIL

Χ2

P

Gender

 Male

132

94(71.2%)

0.06

>0.05

 Female

41

30(73.2%)

Age (Years)

  ≥ 45

118

83(70.3%)

0.33

>0.05

 <45

55

41(74.5%)

AFP (ng/L)

  ≤ 200

23

13(56.5%)

3.11

>0.05

 >200

57

20(35.1%)

Tumor Size (cm)

  ≤ 3

24

12(50.0%)

1.14

>0.05

 >3~ 10

41

15(36.6%)

 >10

15

6(40.0%)

Grade of Differentiation

 Well-differentiated

18

13(72.2%)

0.07

>0.05

 Moderately-differentiated

110

77(70.0%)

 Poorly-differentiated

39

28(71.2%)

Portal Vein Tumor Thrombus

 Yes

33

30(91.0%)

15.44

<0.01

 NO

40

19(47.5%)

Serosal Infiltration

 Yes

35

28(80.0%)

12.64

<0.01

 NO

30

11(36.7%)

Distant Metastasis

 Yes

29

23(80.6%)

9.79

<0.01

 NO

20

7(35.0%)