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Table 1 Properties of polymeric nanoparticles

From: Optimizing cisplatin delivery to triple-negative breast cancer through novel EGFR aptamer-conjugated polymeric nanovectors

PNP formulation

PNPs characteristics

 

Average size (nm)

PDI

Zeta potential (mV)

Drug/Dye concentration

Dry matter amount (mg/ml)

Cis-Pt@PNPs

90.3 ± 0.3

0.254

-21.4

460.78 µM (0.138 µg/µl)

7

Cis-Pt@PNPs-CL4

91.1 ± 1.4

0.290

-12.2

422.70 µM (0.127 µg/µl)

7

Cis-Pt@PNPs-SCR

118.5 ± 20

0.290

-11.1

455.18 µM (0.136 µg/µl)

7

BODIPY@PNPs

97.6 ± 0.3

0.142

0.08

166 µM

8

BODIPY@PNPs-CL4

131.9 ± 0.2

0.185

-17.9

13.6 µM

5

BODIPY@PNPs-SCR

142.2 ± 1.5

0.185

-23.4

9.7 µM

5

Cy7@PNPs

90.5 ± 0.5

0.218

-24.9

104.16 µM

4

Cy7@PNPs-CL4

107.9 ± 0.3

0.350

-20.6

106.8 µM

6

Cy7@PNPs-SCR

104.2 ± 2.7

0.350

-20.6

105.96 µM

6