Fig. 2

a High-throughput RT-qPCR/RNA-seq correlation over the top-42 DEGs. Simple linear regression (95% confidence interval in grey) was performed for resistant (triangles) and sensitive (circles) subjects, respectively. Pearson correlation is estimated as regression curve slope. Each regression also reports 95% confidence intervals of the estimates (95% CI) and corresponding P-values. b Volcano plot of the HT RT-qPCR data. The plot reports the negative log10 of the Benjamini-Hochberg adjusted P value against the log2 fold-change (resistant vs. sensitive). The significance level for gene regulation is set to 0.05. Each gene is a dot, highlighted in blue for down-regulated genes, red for up-regulated, and grey for not-regulated ones