Fig. 9From: The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancerDiagram of the regulatory mechanism through which EFTUD2 attenuates the chemotherapy efficacy of 5-FU by preventing UPS-mediated degradation of c-MYC in CRCBack to article page