Fig. 2

The RPTOR-promoted traverse of lung cancer cells to the BBB. A, B Transwell assays showed that RPTOR promoted the migration and invasion of lung cancer cell lines. C, D Western blotting reported that RPTOR increased EMT-related proteins and extracellular matrix. E, F, G Fluorescence microscope transwell assays showed that RPTOR promoted the traverse of lung cancer cells to the BBB