Fig. 6

EFEMP1 expression in primary tumours correlates with poor prognosis in OS patients. A Representative images of EFEMP1 staining and H&E in biopsy samples of high-grade OS patients at x100 magnification (Scale bar: 50 μm). B, C Kaplan-Meier analysis of overall survival in chondroblastic, fibroblastic and osteoblastic OS patient samples (n = 73 patients) and with metastatic disease (n = 37 patients). Scan cut-off was used to group samples into high (blue) and low (red) EFEMP1 expressions. p-values were determined by a log-rank test