Fig. 8From: Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axisAction of PDAC-derived exosomes on DRG. PDAC of Gli1 overexpression-derived exosomes that were ingested by DRG cells. The has-circ-0011538 was transferred to DRG cells and competed with miR-451a for binding to VGF, which regulated the nerve alterations (figure created with Figdraw)Back to article page