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Fig. 8 | Journal of Experimental & Clinical Cancer Research

Fig. 8

From: A novel PDPN antagonist peptide CY12-RP2 inhibits melanoma growth via Wnt/β-catenin and modulates the immune cells

Fig. 8

CY12-RP2 modifies the proportion of T cells in the spleen and lung of mice. A, B The percentage of CD4 + T cells, CD8 + T cells, and CD4 + CD25 + Foxp3 + Treg cells in the spleen and lung of BALB/c mice were detected by flow cytometry. C Statistical analysis was performed to count the percentage of CD4 + T cells, CD8 + T cells, and CD4 + CD25 + Foxp3 + Treg cells in the spleen and lung of BALB/c mice with lung metastases. D, E Representative triple immunofluorescence of T cells (CD4 + T cells, CD8 + T cells) and CD4 + Foxp3 + Treg cells in the spleen (D) and lung (E) of pulmonary metastasis model. The power field scale bar, 20 μm and 100 μm

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