Fig. 9

CircGPRC5A induces the growth of CRC cells in vivo. A and B Images of subcutaneous xenograft tumors. C After xenograft implantation, the xenograft tumor growth curve was assessed every 5 days. D Subcutaneous xenograft tumor weights. E The effect of knocking-down circGPRC5A on intrahepatic metastasis. F Images of hematoxylin-and-eosin-stained intrahepatic metastases. G Ki-67 and PPP1CA staining and IHC analysis of subcutaneous xenograft tumors. H Diagram illustrating the role of circGPRC5A in CRC