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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: TrkA promotes MDM2-mediated AGPS ubiquitination and degradation to trigger prostate cancer progression

Fig. 1

AGPS plays a key role in the progression and prognosis of prostate cancer. a The Volcano map of Lable-Free MS after ML210 treatment. b The heatmap of top 100 upregulated and downregulated proteins after ML210 treatment. c KEGG analysis of changes proteins after ML210 treatment. d The overlapping Venn diagrams of peroxisome genes and the top 100 upregulated and downregulated genes after ML210 treatment. e AGPS protein expression in PCa tissues and normal tissues. f. AGPS protein expression in different PCa cell lines. g AGPS IHC staining in PCa and normal tissues. h Statistics of AGPS IHC staining. i, j Survival percentage of high or low AGPS expression groups based on IHC score. k ROC curves demonstrate the sensitivity and specificity of AGPS as a marker for PCa prediction

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