Fig. 2

The increased RGCC is related with TNBC clinical features. A-C Analysis of RGCC expression in human breast cancer subtypes (A) and BC patients with different organ metastases (B, C) based on datasets from the TCGA database. In the boxplot, the middle line represents the median, and the bottom and top line correspond to the 25th and 75th percentiles. D Representative IHC images of RGCC in clinical tumor tissues of TNBC in site and lung metastases (Scale bars, 200 μm). E, F Increased RGCC mRNA expression was in lung metastases compared with other organs metastases or primary tumor based on the analysis of microarray datasets from different metastatic solid tumors. G Kaplan–Meier analysis to show patients’ survival of TNBC with high or low level of RGCC. (^*P < 0.05, ^**P < 0.01, ^***P < 0.001)