Fig. 3

RGCC is a promoter for TNBC lung metastasis. A-D Intravenous injection of indicated TNBC cells with RGCC knockdown or control cells for 30 days, representative bioluminescence imaging (BLI) of lung metastasis (A, C) (n = 7 mice per group), pulmonary surface nodules, H&E images (B, D) (n = 7 mice per group) were shown (scale bars, 200 μm). E–H Experiments described as above, BLI (E) (n = 7 mice per group) (E, G), pulmonary surface nodules, H&E images (F, H) (n = 7 mice per group) in mice injected indicated TNBC cells with or without ectopic RGCC (scale bars, 400 μm). I Kaplan–Meier survival analyses of TNBC metastatic mice indicated as A-H (n = 7 mice per group). (The data are presented as the mean ± SD; ^**P < 0.01, ^***P < 0.001)