Fig. 2
RPS7 is up-regulated in HCC with metastasis and is correlated with poor survival. Sixty pairs of HCC samples and matched adjacent nontumoral tissues (ANT) were used to detect the expression of RPS7. Among which, thirty pairs were tissues came from HCC patients with extrahepatic metastasis and other 30 pairs were from metastasis-free HCC patients, designated as EHMH and MFH, respectively. A The mRNA levels of RPS7 in HCC tissues compared to matched ANT. B The protein levels of RPS7 in HCC tissues compared to matched ANT. C The correlation between RPS7 levels and HCC overall survival was evaluated by KM curve. D Forest plot represented the correlation between RPS7 expression and HCC survival, which was evaluated by using univariate and multivariate Cox regression analyses. *, P < 0.05. E The comparison of RPS7 mRNA levels between EHMH group and MFH group. F RPS7 protein levels in EHMH and MFH were respectively detected by western blot assay, as shown was the representative result. G The comparison of RPS7 protein levels between EHMH group and MFH group. H. The expression and localization of RPS7 in HCC tissues compared to matched ANT were analyzed by Immunohistochemistry