Fig. 5
From: Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy
Control assays using Ru1 derivatives. A Chemical structure of Ru1 and derivatives. B Representative images of Panc185 and PancA6L colonies in the absence (Control) or presence of Ru1 or indicated derivatives (10 and 100µM). Cells were treated for 24 h with the ruthenium compounds at 10 or 100µM during day 1 post seeding. C Mean fold change ± SEM in the colony efficiency (crystal violet absorbance) in treated (10 or 100µM) and Control samples, which were set to 1.0. ** p < 0.01, **** p < 0.0001, ns = not significant, as determined by one-way ANOVA with Dunnett post-test, comparing 10- or 100µM-treated to Control