Fig. 16

TME and spleen immune characterization of K and KL untreated mice: A, B TME immune profile of KRAS^G12D and KRAS^G12D/LKB1^del tumours injected intramuscularly; C, D spleen immune profile of immunocompetent mice bearing KRAS^G12D and KRAS^G12D/LKB1^del tumours; samples from the experiment in Fig. 12 were collected and processed for FACS analysis of lymphoid and myeloid infiltrating immune cells (see Fig. 2 for the gate strategy). One-way and two-way ANOVA were used for statistical analysis (**p < 0.01, ****p < 0.0001). Error bars indicate SD