Fig. 8From: Caloric restriction and metformin selectively improved LKB1-mutated NSCLC tumor response to chemo- and chemo-immunotherapyGraph of body weight of mice bearing K and KL tumors: Body weight of KRASG12D (A) and KRASG12D/LKB1del (B) mice used in Fig. 7 submitted to CR alone or in combination with DDP or/and metformin. The treatment schedule was well-tolerated, as the body weight lost during the fasting period was regain within 24 hBack to article page