Fig. 3

DCAF13 negatively regulates the p53 signaling pathway. A-C. Heat map, volcano map and venn diagram of differential gene expression in A549 cells followed by DCAF13 knockdown (p-adjust< 0.05 and fold change > 2). D. Bubble map of top 20 pathways for all differential genes by GO enrichment analysis. E. Bubble map of top 20 pathways for all differential genes by KEGG enrichment analysis. F. Gene Set Enrichment Analysis (GSEA) of the p53 signaling pathway. G. Heat map of p53 downstream 28 genes acting core in the Fig. 3F