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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma

Fig. 5

DCAF13 knockdown alters histone modifications of p53 target genes. A-D. The p53-RE positions in BAX, CDKN1A, PIDD1, FAS promoter regions and alterations of H3K4me3, H3K9me3 or H3K27me3 on p53-RE by ChIP-qPCR in shControl or shDCAF13 A549 cells. Data were statistically analyzed using Student’s t-test and values are shown as mean ± SD. * p < 0.05, ** p < 0.01, and *** p < 0.001

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