Skip to main content
Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: LncRNA AL139294.1 can be transported by extracellular vesicles to promote the oncogenic behaviour of recipient cells through activation of the Wnt and NF-κB2 pathways in non-small-cell lung cancer

Fig. 2

Knockdown of AL139294.1 inhibits the tumorigenic capacities of the NSCLC cells. A The levels of AL139294.1 in Beas-2B and NCI-H1299 cells were quantified after the transfection of si-NC, si76, si202, and si337. The effects of AL139294.1 knockdown on the proliferation ability of Beas-2B (B) and NCI-H1299 (C) cells were examined by CCK-8 assay. Wound healing assay (D) and transwell assay (E) were used to evaluate the migration and invasion abilities of Beas-2B and NCI-H1299 cells. F EMT-related markers were detected by western blotting in Beas-2B and NCI-H1299 cells after the knockdown of AL139294.1. G Colony formation assay was used to detect the clone formation ability of Beas-2B and NCI-H1299 cells after AL139294.1 knockdown. H Flow cytometry was performed to evaluate the effect of AL139294.1 knockdown on cells’ apoptosis. **P < 0.01

Back to article page

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us