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Fig. 9 | Journal of Experimental & Clinical Cancer Research

Fig. 9

From: LncRNA AL139294.1 can be transported by extracellular vesicles to promote the oncogenic behaviour of recipient cells through activation of the Wnt and NF-κB2 pathways in non-small-cell lung cancer

Fig. 9

Schematic diagram. EVs carrying AL139294.1 are secreted by the origin cells and enter the recipient cells. In the cytoplasm of recipient cells, AL139294.1 is released. It interacts with miR-204-5p, leading to the derepressing of miR-204-5p on its target BRD4, which further activates the Wnt5a and NF-κB2 signaling pathways and finally contributes to the progression of NSCLC

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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