Fig. 6

MAGOH inhibited hnRNPA1 expression and hnRNPA1 binding to RON mRNA. A Heatmap of differentially expressed genes (DEGs) between AGS cells with low MAGOH expression and control cells. B Heatmap of the expression profiles of splicing factors showing significant differences between AGS cells with low MAGOH expression and control cells. C, D The correlation between the expression of MAGOH and hnRNPA1 in GC cells transfected with MAGOH siRNA was examined by qRT‒PCR and WB. E, F The correlation between the expression of MAGOH and hnRNPA1 in GC cells transfected with the MAGOH overexpression plasmid was examined by qRT‒PCR and WB. G, H The correlation between the expression of MAGOH and hnRNPA1 in the sh-NC group, sh-MAGOH group and sh-MAGOH + MAGOH overexpression plasmid cotransfected group was examined by qRT‒PCR and WB